REMICADE

Risperidone is an antipsychotic agent belonging to a new chemical class, the benzisoxazole derivatives. The chemical designation is :

3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a] pyrimidin-4-one.
Its molecular formula is C23H27FN4O2 and its molecular weight is 410.49.

Risperidone is a white to slightly beige powder. It is practically insoluble in water, freely soluble in methylene chloride, and soluble in methanol and 0.1 N HCl.

Risperdal tablets are available in 0.25 mg (dark yellow), 0.5 mg (red-brown), 1 mg (white), 2 mg (orange), 3 mg (yellow), and 4 mg (green) strengths. Inactive ingredients are colloidal silicon dioxide, hydroxypropyl methylcellulose, lactose, magnesium stearate, microcrystalline cellulose, propylene glycol, sodium lauryl sulfate, and starch (corn). Tablets of 0.25, 0.5, 2, 3, and 4 mg also contain talc and titanium dioxide. The 0.25 mg tablets contain yellow iron oxide, the 0.5 mg tablets contain red iron oxide; the 2 mg tablets contain FD&C yellow no. 6 aluminum lake; the 3 mg and 4 mg tablets contain D&C yellow no. 10; the 4 mg tablets contain FD&C blue no. 2 aluminum lake.

Risperidone is also available as a 1 mg/ml oral solution. The Inactive Ingredients for This Solution Are: Tartaric acid, benzoic acid, sodium hydroxide and purified water.
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